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I did the same with an M4400 (same gen as E6400 and very similar internals) and the results are great. It might be that the weaker GPU on the E6400 will lag a bit with Win10 but I'd be surprised if it is much. I'm going to do an E6400 switchover soon since the M4400 went so well. Just do a clean install, not the upgrade, for a good result. Another thought: throw an SSD, even a cheap one, in there and you'll give that old machine a lot more zip. As long as you know your Win7 key you can do a clean install from the current Win10 ISO that you can get from here. Another suggestion, while you've got it open to install that SSD repaste the CPU on it with some good thermal paste (and blow out all the dust): you might get it working so cool that you can experiment with a little overclocking and/or undervolting.